Watery Diarrhea: V. Cholerae/Cholera Toxin
Über den Vortrag
Der Vortrag „Watery Diarrhea: V. Cholerae/Cholera Toxin“ von John Fisher, MD ist Bestandteil des Kurses „Year 3 – Internal Medicine“.
Quiz zum Vortrag
Which of the following describes the typical stool of a person infected with Vibrio cholerae?
- Rice water appearance
- Malodorous
- Bloody
- Mucousy
- Purulent
What is the function of the B subunit of the cholera toxin?
- Creates a pore in the intestinal mucosal cell wall to allow active toxin to enter the cell
- It is the active toxic component of the pathogen
- Enters the endoplasmic reticulum
- Releases sodium ions into the intestinal lumen
- Binds to cyclic AMP
What is the mechanism causing diarrhea in patients with cholera?
- Secretes electrolytes into the gut lumen causing water to follow
- Flattens the intestinal brush border
- Acts as a bulk forming laxative
- Stimulates intestinal peristalsis
- The bacteria invades the mucosa and causes inflammatory diarrhea
What is the mechanism of morbidity and mortality in patients infected by cholerae?
- Hypovolemic shock
- Toxic shock
- Cardiogenic shock
- Fulminant liver failure
- Cardiorespiratory failure
What is the appropriate treatment for a patient suffering from severe cholerae?
- Azithromycin and rapid intravenous electrolyte and fluid replacement
- Clindamycin and oral hydrataion
- Fosfomycin and gentle intravenous fluid replacement
- Only rapid intravenous hydration is neccessary to hydrate the patient and wash out the bacteria
- Flouroquinolone and anti-diarrheal medications
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Dozent des Vortrages Watery Diarrhea: V. Cholerae/Cholera Toxin
John Fisher, MD
Dr. John F. Fisher is a Professor of Medicine and Infectious Diseases at the Medical College of Georgia, Augusta University in the USA.
He obtained his medical degree from Virginia Commonwealth University School of Medicine in 1969. He is a Master of the American College of Physicians (MACP) and is certified by the American Board of Internal Medicine in Medicine and Infectious Diseases.
Due to his achievements, he has earned the Annual J. Willis Hurst Teaching Award, the Jane F. Deforges Excellence in Medical Education Award, and the Infectious Diseases Society of America's Clinical Teacher Award.
Within Lecturio, Dr. Fisher teaches courses on Infectious Diseases.
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